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wisp-science

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Open-source, local-first desktop AI research workbench for scientific computing with Python/R, MCP bioinformatics tools, SSH/WSL/GPU runtimes, and OpenAI/Anthropic models.

★ 1.2K122 forksRustAGPL-3.0xuzhougeng

Local-first desktop AI research workbench (Rust/Tauri) where an agent runs Python and R, queries ~80 scientific databases through bundled MCP servers, and executes jobs on local, WSL, SSH or GPU hosts. Bring your own OpenAI-compatible or Anthropic model; data, keys and history stay on your machine.

Use Cases

Run RNA-seq and other scientific analyses with an AI agentSearch PubMed, GEO and ~80 scientific databases via bundled MCP serversExecute Python and R in persistent isolated kernels per conversationSubmit long-running jobs on local, WSL, SSH and GPU hosts with live logsFreeze manuscript revisions into verifiable Evidence CapsulesExplore alternative research directions in isolated branchesReuse project Skills (SKILL.md) without flooding the promptKeep literature, figures, runs and drafts in one local project

Built With

Language
Rust
Frameworks
Tauri · Rust · Tokio · axum · serde · reqwest · MCP · ACP (agent-client-protocol)

Tags

local-first · desktop-app · scientific-computing · bioinformatics · mcp · agent-skills · python · r · ssh · gpu · wsl · rust · tauri · research-assistant · reproducible-research · acp